Product Name
Etodolac
CAS Number
41340-25-4
Molecular Formula
C17H21NO3
Appearance
White or off-white crystalline powder
Description
Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzymes cyclooxygenase (COX-1 and COX-2), which play a key role in the production of prostaglandins. Prostaglandins are compounds involved in inflammation, pain, and fever, making them a target for pain management. Etodolac selectively inhibits COX-2, which is primarily responsible for inflammation and pain, while sparing COX-1, which protects the gastrointestinal lining. This selectivity results in effective pain relief with a lower risk of gastrointestinal side effects compared to traditional NSAIDs.
Uses
Pain and Inflammation Relief
Used for managing mild to moderate pain in conditions like postoperative pain, dental pain, and musculoskeletal injuries.
Provides long-lasting analgesic effects due to its extended half-life.
01
Arthritis Treatment
Effective in reducing joint pain, stiffness, and inflammation in osteoarthritis and rheumatoid arthritis.
Helps improve mobility and quality of life in patients with chronic inflammatory joint diseases.
02
Postoperative and Injury Management
Commonly prescribed after surgeries or injuries to control swelling and pain.
Used in sports medicine for treating tendonitis, bursitis, and sprains.
03
Fever Reduction
Exhibits antipyretic effects, making it useful for reducing fever in certain medical conditions.
04
Lower Gastrointestinal Risk
Compared to traditional NSAIDs, Etodolac has a more selective COX-2 inhibition, potentially lowering the risk of gastric irritation and ulcers.
05
Quality Standards
- Standards: Conforms to USP and EP
- Purity: ≥ 98%
- Identification: Meets USP/BP/EP standards
- Heavy Metals: Lead ≤ 10 ppm, Arsenic ≤ 3 ppm, Cadmium ≤ 1 ppm
- Loss on Drying: ≤ 1.0%
- Microbial Limits: Total Plate Count ≤ 1000 cfu/g, E. coli Negative, Salmonella Negative
Storage Conditions
- Store in a cool, dry place, away from direct sunlight and moisture.
- Keep the container tightly sealed to prevent degradation.
- Recommended storage temperature: 15-25°C.
- Protect from excessive heat and humidity to maintain stability.
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