Product Name
Metronidazole Tablets
Composition
Active Ingredient: Metronidazole
Appearance
White to off-white, round, biconvex, film-coated tablets.
Dosage Form
Oral Tablets
Specifications
250 mg per tablet 500 mg per tablet
(Other custom specifications available upon request)
Indications
Metronidazole Tablets are a broad-spectrum antimicrobial agent used to treat a variety of bacterial and protozoal infections. It works by inhibiting the growth of microorganisms, particularly anaerobic bacteria and certain protozoa, by disrupting their DNA synthesis.
Bacterial Infections:
Metronidazole is effective in treating a wide range of bacterial infections, especially those caused by anaerobic bacteria. It is commonly prescribed for:
Intra-abdominal Infections
Gynecological Infections: Including bacterial vaginosis and pelvic inflammatory disease (PID) caused by anaerobic bacteria.
Skin and Soft Tissue Infections: Particularly those caused by anaerobes like Bacteroides and Clostridium species.
Respiratory Tract Infections: Such as aspiration pneumonia and lung abscesses.
Dental Infections: Used for treating infections of the teeth and gums caused by anaerobic bacteria.
Protozoal Infections
Metronidazole is effective against several protozoan infections, including:
Giardiasis: A parasitic infection of the intestine caused by Giardia lamblia.
Amoebiasis: Including both intestinal and extra-intestinal forms caused by Entamoeba histolytica.
Trichomoniasis: A sexually transmitted infection caused by the protozoan Trichomonas vaginalis.
Balantidiasis: An intestinal infection caused by Balantidium coli.
Clostridial Infections
Metronidazole is used to treat infections caused by Clostridium species, including Clostridium difficile infections, which can lead to severe diarrhea and colitis.
Post-surgical Prophylaxis
Metronidazole is often used as part of a combined regimen to prevent infections after surgery, particularly in colorectal and gynecological surgeries, where anaerobic bacteria are common pathogens.
Helicobacter pylori Eradication
In combination with other antibiotics and proton pump inhibitors, Metronidazole is used to eradicate Helicobacter pylori, a bacterium associated with peptic ulcers.
Rosacea (Topical or Oral Use)
Though usually treated topically, oral Metronidazole may be prescribed for severe cases of rosacea to help reduce the inflammatory symptoms.
Standard
Conforms to USP and EP.
Storage Conditions
- Store at 15°C to 25°C (59°F to 77°F).
- Keep in a cool, dry place, away from moisture, heat, and direct sunlight.
- Store in its original packaging to maintain stability and potency.
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