Product Name

Bempedoic Acid

CAS Number

1219479-06-4

Molecular Formula

C17H21ClO4

Appearance

White to off-white crystalline powder

Description

Bempedoic acid is a medication used to lower LDL cholesterol in patients with hyperlipidemia. It works by inhibiting the ATP-citrate lyase (ACL) enzyme, which plays a key role in cholesterol synthesis in the liver. By targeting this enzyme, Bempedoic acid reduces the production of cholesterol, leading to lower levels of LDL cholesterol in the bloodstream. It is used as part of a comprehensive treatment plan, often in combination with other cholesterol-lowering medications, to help reduce the risk of cardiovascular events like heart attacks and strokes.

Uses

Treatment of Hyperlipidemia

Bempedoic acid is used to treat hyperlipidemia, specifically elevated LDL cholesterol, in patients who require additional lowering of cholesterol levels beyond diet and lifestyle changes. It is particularly beneficial for patients who cannot tolerate statins due to side effects, offering an alternative to manage cholesterol levels effectively.

Adjunctive Therapy with Statins or Other Cholesterol-Lowering Agents

Bempedoic acid is frequently used in combination with statins, ezetimibe, or other lipid-lowering agents to provide enhanced cholesterol reduction. It works synergistically with these medications to further lower LDL cholesterol and reduce overall cardiovascular risk.

Prevention of Cardiovascular Events

By effectively lowering LDL cholesterol, Bempedoic acid can help reduce the risk of cardiovascular events such as heart attacks, strokes, and other complications related to atherosclerosis in high-risk patients. It is used to manage patients with a history of cardiovascular disease or those at high risk due to conditions like diabetes and hypertension.

Quality Standards

Manufactured in GMP-certified facilities, ensuring adherence to rigorous standards of quality and safety.
Complies with international pharmacopoeial standards (USP, EP) for purity, potency, and consistency.
Purity ≥98%, with comprehensive testing for impurities, stability, and potency to ensure optimal therapeutic performance.

Storage Conditions

Store in a cool, dry place at a temperature between 20°C to 25°C.
Protect from light and moisture to preserve the stability and potency of the product.
Keep tightly closed in the original container to prevent contamination and ensure the integrity of the product over its shelf life.

References：

Thompson, S., et al. "Bempedoic acid efficacy and safety in hypercholesterolemia: a systematic review and metaanalysis." Journal of the American College of Cardiology. 2022.

Hot Tags: bempedoic acid, China bempedoic acid manufacturers, suppliers, Meropenem for Injection, Etamsylate Injection, Fructose Sodium Diphosphate for Injection, Compound Amino Acid Injection, Betahistine 68 94 0, Methylphenidate Hydrotalcite 129495 26 3