Product Name

Azithromycin

CAS Number

83905-01-5

Molecular Formula

C38H72N2O12

Appearance

White to off-white crystalline powder

Description

Azithromycin is a broad-spectrum macrolide antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial protein synthesis, which prevents bacterial growth. Azithromycin is known for its long half-life, allowing for shorter treatment regimens compared to other antibiotics.

Uses

Respiratory Tract Infections

Community-Acquired Pneumonia (CAP): Effective against common pathogens like Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae.

Acute Otitis Media (AOM): Used for middle ear infections, especially in children, caused by Streptococcus pneumoniae and Moraxella catarrhalis.

Chronic Sinusitis: Treats bacterial sinus infections, especially those resistant to other antibiotics.

Skin and Soft Tissue Infections

Treats conditions such as cellulitis, impetigo, and abscesses, often caused by Staphylococcus aureus and Streptococcus pyogenes.

Sexually Transmitted Infections (STIs)

Chlamydia Trachomatis: Azithromycin is a first-line treatment for chlamydia infections, commonly used for both men and women.

Gonorrhea: Used in combination with other antibiotics to treat Neisseria gonorrhoeae infections.

Syphilis: In some cases, azithromycin may be used as an alternative treatment for syphilis.

Gastrointestinal Infections

Treats infections caused by Campylobacter jejuni and Shigella species, which can lead to bacterial gastroenteritis.

Prophylaxis and Prevention

Malaria: Azithromycin is sometimes used in combination with other drugs for malaria prophylaxis in travelers.

Prevention of Mycobacterium Avium Complex (MAC): Used in HIV-infected patients to prevent infection by Mycobacterium avium.

Chronic Obstructive Pulmonary Disease (COPD)

Used as part of a treatment regimen to reduce the frequency of exacerbations in patients with COPD.

Quality Standards

Standards: Conforms to USP and EP
Purity: ≥ 98%
Heavy Metals: Lead ≤ 10 ppm, Arsenic ≤ 3 ppm, Cadmium ≤ 1 ppm
Microbial Limits: Total Plate Count ≤ 1000 cfu/g, E. coli Negative, Salmonella Negative
Solubility: Soluble in water, methanol, and ethanol.