Product Name
Sodium Carboxymethyl Starch (CMS)
CAS Number
9063-38-1
Molecular Formula
(C6H10O5)n·(C2H3NaO2)m
Appearance
White to off-white, free-flowing powder
Description
Sodium Carboxymethyl Starch (CMS) is a modified starch, derived from natural starch sources, typically corn or potato. It is produced by reacting starch with monochloroacetic acid in the presence of sodium hydroxide, which results in the introduction of carboxymethyl groups into the starch molecule. This modification improves its solubility and functionality compared to native starch. CMS is highly water-soluble, non-toxic, and has a neutral pH when dissolved in water.
Uses
Pharmaceutical Industry
Disintegrant: Used as a disintegrant in tablet formulations, CMS promotes the rapid breakdown of tablets upon ingestion, ensuring the effective release of active ingredients.
Binder and Excipient: It serves as a binder and excipient in solid dosage forms, helping to improve the integrity of tablet and capsule formulations.
Suspending Agent: CMS is used in liquid formulations to suspend insoluble drugs, improving the stability and homogeneity of suspensions.
Stabilizer for Injectables: In injectable formulations, CMS is used as a stabilizing agent for active pharmaceutical ingredients, ensuring the stability and efficacy of the product over time.
01
Food Industry
As a food additive, CMS is used as a thickening and stabilizing agent in processed foods, such as sauces, dressings, and soups.
02
Cosmetic Industry
Used in personal care formulations for its binding and thickening properties, CMS is found in creams, lotions, and other topical products.
03
Textile and Paper Industries
CMS is employed as a sizing agent in the textile industry, improving the strength and durability of fabrics. It is also used in paper manufacturing to enhance the texture and quality of paper.
04
Quality Standards
- Purity: Minimum 95% (dry basis)
- Standards: Conforms to USP and EP
- Microbial Limits: Meets pharmacopeial requirements (e.g., total plate count, yeast, and molds)
Storage Conditions
- Store in a cool, dry place, away from direct sunlight and moisture.
- Keep containers tightly closed to avoid contamination and degradation of the product.
- Recommended storage temperature: 15°C - 25°C.
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