Product Name
KLEPTOSE-ROQUETTE
CAS Number
94035-02-6
Molecular Formula
(C₆H₁₀O₅)ₙ · (C₆H₁₁O₃)ₙ
Appearance
White to off-white, odorless, fine powder or slightly crystalline powder, freely soluble in water.
Description
KLEPTOSE is a derivative of β-cyclodextrin, produced by substituting some of the hydroxyl groups on the β-cyclodextrin molecule with hydroxypropyl groups. This modification enhances its solubility in water, making it more suitable for pharmaceutical, food, and cosmetic applications. KLEPTOSE is commonly used to improve the solubility and stability of poorly soluble compounds, particularly in the pharmaceutical industry, where it serves as a carrier for drug delivery.
Uses
Pharmaceuticals
Drug Solubilizer and Stabilizer: KLEPTOSE is widely used to enhance the solubility and bioavailability of poorly water-soluble drugs. It forms inclusion complexes with hydrophobic drugs, improving their stability and dissolution rate. This is particularly important in the formulation of oral, injectable, and topical drug products.
Controlled Drug Release: It is employed in controlled-release drug formulations, where it helps to modulate the release rate of active pharmaceutical ingredients (APIs), improving the therapeutic efficacy of drugs over time.
Taste Masking Agent: KLEPTOSE is used to mask the bitter taste of certain drugs, particularly in pediatric formulations or chewable tablets.
Ophthalmic Solutions: KLEPTOSE is used in ophthalmic formulations for improved solubility of active ingredients like corticosteroids, antifungal agents, and antibiotics.
Cosmetics and Personal Care
Carrier for Active Ingredients: KLEPTOSE is used in cosmetic formulations as a carrier to improve the stability, solubility, and controlled release of active ingredients, such as vitamins, peptides, and antioxidants.
Skin Penetration Enhancer: It helps improve the skin penetration of certain active compounds in topical skincare products, promoting their effectiveness.
Fragrance Stabilizer: KLEPTOSE is used to stabilize fragrances in personal care products, preventing their premature evaporation and improving their longevity.
Quality Standards
- Standards: Conforms to USP and EP
- Purity: ≥ 98%
- Microbial Limits: Meets acceptable microbial limits for excipients
Storage Conditions
- Store in a cool, dry place, away from moisture and direct sunlight.
- Keep in a tightly sealed container to prevent contamination and moisture absorption.
- Recommended storage temperature: 15–25°C.
- Ensure proper ventilation in storage areas.
- Avoid exposure to strong oxidizing agents or incompatible materials.
https://www.ncbi.nlm.nih.gov/search/all/?term=KLEPTOSE
Hot Tags: kleptose-roquette, China kleptose-roquette manufacturers, suppliers, liquids for injection, Ibuprofen Lysine, Dextrin 9004 53 9, Paracetamol Tablets, Meropenem for Injection, Methyl Dopa 555 30 6
