What should be noted when taking nifedipine?

Short acting tablets should be taken three times a day (morning, afternoon, and evening), and short acting drugs should not be taken orally. Extended release tablets should be taken twice a day (morning and evening), while controlled-release tablets should be taken once a day (morning). Note that short and medium acting tablets should not be taken only once a day, as this can cause blood pressure fluctuations and lower blood pressure instability.
Nifedipine also has adverse reactions, although the incidence is low, it should be understood. It takes 30 minutes to take the first dose, and some people may experience facial flushing, facial heat, and increased heart rate. Long term use can lead to lower limb edema, gum swelling, and hyperplasia. These adverse reactions are functional and will gradually disappear after discontinuation of medication. Some individuals may experience urinary retention after taking short acting and sustained-release medications.
3. Taking long-acting controlled-release tablets can only last for 24 hours, and the medication time on the second day cannot be postponed (such as taking the medication at 7am and not taking it at 8am or 9am the next day) because the drug concentration is only 24 hours. Delaying medication can lead to an increase in blood pressure within 1-2 hours. In addition, Nifedipine controlled-release tablets are not suitable for patients with chronic diarrhea because the drug is released at a fixed time and rate in the intestine. When diarrhea occurs, the intestinal peristalsis accelerates and the drug is excreted, which cannot exert its antihypertensive effect.
4. What are the most suitable groups for taking nifedipine: the elderly, people with carotid atherosclerosis or plaque, people who eat more salt or are salt sensitive, hypertensive patients with coronary heart disease and angina pectoris, refractory hypertension, etc. Because of its anti atherosclerosis clinical trials, the effect of statin on patients with atherosclerosis will be better. There are also studies that have shown that the effect of preventing stroke is better than other antihypertensive drugs. In addition, combination therapy is recommended for patients whose blood pressure does not meet the standard after taking this medication. For patients with cardiovascular and renal diseases, combination therapy with sartan or pril drugs can be used. For patients with coronary heart disease, B-receptor blockers can also be used.